Title :
Towards fast solid state DNA sequencing
Author :
Purushothaman, S. ; Toumazou, C. ; Georgiou, J.
Author_Institution :
Dept. of Electr. & Electron. Eng., Imperial Coll. of Sci., Technol. & Med., London, UK
Abstract :
The current most widely used method for DNA sequencing is the chain termination method or Sanger technique. Many attempts are being made to improve upon this method particularly with regard to the elimination of the latter stage of electrophoresis. Using the ion sensitive field effect transistor and low power signal processing techniques, the possibility of intelligent solid state DNA sequencing is explored.
Keywords :
DNA; biological techniques; biomolecular electronics; digital signal processing chips; ion sensitive field effect transistors; low-power electronics; DNA chips; ISFET; chain termination method; electrophoresis; fast solid state DNA sequencing; intelligent sequencing; ion sensitive field effect transistor; low power signal processing techniques; nucleotide base; Biochemistry; Biomedical signal processing; Biosensors; DNA; Electrokinetics; FETs; Hydrogen; Sequences; Solid state circuits; Termination of employment;
Conference_Titel :
Circuits and Systems, 2002. ISCAS 2002. IEEE International Symposium on
Print_ISBN :
0-7803-7448-7
DOI :
10.1109/ISCAS.2002.1010416
