Title :
Simulation of Biochemical Networks using Copasi - A Complex Pathway Simulator
Author :
Sahle, Sven ; Gauges, Ralph ; Pahle, Jurgen ; Simus, Natalia ; Kummer, Ursula ; Hoops, Stefan ; Lee, Christine ; Singhal, Mudita ; Xu, Liang ; Mendes, Pedro
Author_Institution :
Dept. of Bioinformatics & Comput. Biochem., EML Res., Heidelberg
Abstract :
Simulation and modeling is becoming one of the standard approaches to understand complex biochemical processes. Therefore, there is a big need for software tools that allow access to diverse simulation and modeling methods as well as support for the use of these methods. Here, we present a new software tool that is platform independent, user friendly and offers several unique features. In addition, we discuss numerical considerations and support for the switching between simulation methods
Keywords :
biochemistry; biology computing; digital simulation; software tools; COPASI; biochemical networks; complex pathway simulator; modeling; simulation; software tools; Analytical models; Bioinformatics; Computational modeling; Linux; Mathematical model; Parameter estimation; Software tools; Steady-state; Stochastic processes; Switches;
Conference_Titel :
Simulation Conference, 2006. WSC 06. Proceedings of the Winter
Conference_Location :
Monterey, CA
Print_ISBN :
1-4244-0500-9
Electronic_ISBN :
1-4244-0501-7
DOI :
10.1109/WSC.2006.322945
