Title :
A spatial filtering forward and inverse model of EEG and MEG
Author :
Bradshaw, L.A. ; Wijesinghe, R.S. ; Wikswo, J.P., Jr.
Author_Institution :
Dept. of Phys. & Astron., Vanderbilt Univ., Nashville, TN, USA
Abstract :
The electroencephalogram (EEG) and the magnetoencephalogram (MEG) recorded outside the human head are the result of underlying neural activity in the cortex. The process of determining the neural sources from the measured EEG and/or MEG is known as the inverse problem. Given the source distribution, the forward problem may be solved by electromagnetic field theory, which relates the sources to the electric potential and magnetic field by Green´s functions. Inversion of the Green´s function is then necessary to perform the inverse procedure. Since this inversion generally results in instability, the inverse Green´s function must be regularized. Examination of the regularization of the inverse problem reveals important information about the spatial resolving power, the accuracy of the inverse calculation and its sensitivity to noise
Keywords :
Green´s function methods; electroencephalography; inverse problems; magnetoencephalography; physiological models; EEG; MEG; electric potential; human head; inverse Green´s function; inverse calculation accuracy; magnetic field; neural sources determination; noise sensitivity; regularized function; spatial filtering forward/inverse model; spatial resolving power; Brain modeling; Electroencephalography; Electromagnetic measurements; Filtering; Green´s function methods; Humans; Inverse problems; Magnetic field measurement; Magnetic heads; Magnetic separation;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.411800