Title :
Gadolinium-containing inorganic nanostructures for biomedical applications: Cytotoxic aspects
Author :
Hemmer, Eva ; Yamano, Tomoyoshi ; Kishimoto, Hidehiro ; Soga, Kohei
Author_Institution :
Dept. of Mater. Sci. & Technol., Tokyo Univ. of Sci., Chiba, Japan
Abstract :
Bioimaging is an important tool for investigation and visualization of biological phenomena and as diagnostic tool in medicine. In this context upconverting Gd2O3:Er3+, Yb3+ nanostructures (nanoparticles, nanorods) have been synthesized and investigated with regard to potential biomedical applications. Besides size and morphology effect on cytotoxic behavior, the influence of PEG-b-PAAc surface modification on biocompatibility was analyzed.
Keywords :
biomedical materials; cellular biophysics; erbium; gadolinium compounds; nanofabrication; nanomedicine; nanoparticles; nanorods; surface morphology; ytterbium; Gd2O3:Er,Yb; PEG-b-PAAc surface modification; biocompatibility; bioimaging; biological visualization; biomedical applications; cytotoxic behavior; diagnostic tool; gadolinium-containing inorganic nanostructures; medicine; nanoparticles; nanorods; surface morphology; Chemicals; Fluorescence; Morphology; Nanobioscience; Nanoparticles; Surface morphology; Gadolinium oxide; bioimaging; cytotoxicity; surface modification; upconversion;
Conference_Titel :
Nanoscience and Nanotechnology (ICONN), 2010 International Conference on
Conference_Location :
Sydney, NSW
Print_ISBN :
978-1-4244-5261-3
Electronic_ISBN :
978-1-4244-5262-0
DOI :
10.1109/ICONN.2010.6045165
