Gadolinium-containing inorganic nanostructures for biomedical applications: Cytotoxic aspects

Author

Hemmer, Eva ; Yamano, Tomoyoshi ; Kishimoto, Hidehiro ; Soga, Kohei

Author_Institution

Dept. of Mater. Sci. & Technol., Tokyo Univ. of Sci., Chiba, Japan

fYear

2010

fDate

22-26 Feb. 2010

Firstpage

225

Lastpage

229

Abstract

Bioimaging is an important tool for investigation and visualization of biological phenomena and as diagnostic tool in medicine. In this context upconverting Gd₂O₃:Er³⁺, Yb³⁺ nanostructures (nanoparticles, nanorods) have been synthesized and investigated with regard to potential biomedical applications. Besides size and morphology effect on cytotoxic behavior, the influence of PEG-b-PAAc surface modification on biocompatibility was analyzed.

Keywords

biomedical materials; cellular biophysics; erbium; gadolinium compounds; nanofabrication; nanomedicine; nanoparticles; nanorods; surface morphology; ytterbium; Gd₂O₃:Er,Yb; PEG-b-PAAc surface modification; biocompatibility; bioimaging; biological visualization; biomedical applications; cytotoxic behavior; diagnostic tool; gadolinium-containing inorganic nanostructures; medicine; nanoparticles; nanorods; surface morphology; Chemicals; Fluorescence; Morphology; Nanobioscience; Nanoparticles; Surface morphology; Gadolinium oxide; bioimaging; cytotoxicity; surface modification; upconversion;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanoscience and Nanotechnology (ICONN), 2010 International Conference on

Conference_Location

Sydney, NSW

Print_ISBN

978-1-4244-5261-3

Electronic_ISBN

978-1-4244-5262-0

Type

conf

DOI

10.1109/ICONN.2010.6045165

Filename

6045165