• DocumentCode
    1817432
  • Title

    Magnetic resonance-electrical impedance tomography in breast cancer imaging

  • Author

    Birgul, Ozlem ; Hamamura, Mark J. ; Muftuler, L. Tugan ; Nalcioglu, Orhan

  • Author_Institution
    Tu & Yuen Center for Functional Onco Imaging, California Univ., Irvine, CA
  • fYear
    2006
  • fDate
    6-9 April 2006
  • Firstpage
    686
  • Lastpage
    689
  • Abstract
    Magnetic resonance - electrical impedance tomography employs low amplitude currents injected or induced inside an object. The additional magnetic field due to these currents results in a phase in the MR images. A modified fast spin-echo sequence is used to measure this magnetic field, which is simply the scaled phase MR image. Finite element method is used for the solution of the forward problem. An iterated sensitivity matrix based algorithm was developed for the inverse problem. Resulting ill-conditioned matrix equation was regularized using Tikhonov method and solved using a conjugate gradient solver. After assessing the performance of the technique with agarose gel phantoms, we carried out experiments on rats with induced tumor to understand the in-vivo performance of this system
  • Keywords
    biological organs; biomagnetism; biomedical MRI; cancer; conjugate gradient methods; electric impedance imaging; finite element analysis; gynaecology; inverse problems; medical image processing; phantoms; spin echo (NMR); tumours; Tikhonov regularization; agarose gel phantoms; breast cancer imaging; conjugate gradient solver; finite element method; forward problem; inverse problem; iterated sensitivity matrix; magnetic field; magnetic resonance-electrical impedance tomography; modified fast spin-echo sequence; rat tumor; scaled phase MR image; Breast cancer; Equations; Finite element methods; Impedance; Inverse problems; Magnetic field measurement; Magnetic resonance; Magnetic resonance imaging; Phase measurement; Tomography;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on
  • Conference_Location
    Arlington, VA
  • Print_ISBN
    0-7803-9576-X
  • Type

    conf

  • DOI
    10.1109/ISBI.2006.1625009
  • Filename
    1625009