Determination of the Lesion Size in Laser-Induced Interstitial Thermal Therapy (LITT) using a Low-Field MRI

Author

Viard, R. ; Emptaz, A. ; Piron, B. ; Rochon, P. ; Wassmer, B. ; Mordon, S.

Author_Institution

Inserm, U703, Lille

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

214

Lastpage

217

Abstract

This study aimed to compare MR thermal mapping during laser-induced interstitial thermal therapy (LITT) to thermal lesions observed macroscopically, in order to estimate the 3D size of the coagulative necrosis. Laser irradiation was performed ex-vivo with a 980 nm laser in pig liver in a open low-magnetic field (0.2 T) scanner. The laser light was transmitted through a 1040/600 mum (outer/core diameter) bare-tip silica fiber. The laser energy was applied on a pulsed mode (10 s laser-on, 10 s laser-off) for 12 minutes, power: 6 W, energy: 2160 J. MR thermal mapping used T1 method for its simplicity and its efficiency at low magnetic field.

Keywords

biomedical MRI; diseases; laser applications in medicine; liver; radiation therapy; bare-tip silica fiber; coagulative necrosis; laser energy; laser irradiation; laser-induced interstitial thermal therapy; lesion size; low- field magnetic resonance imaging; magnetic flux density 0.2 T; pig liver; power 6 W; thermal lesions; thermal mapping; time 10 s; time 12 min; wavelength 980 nm; Fiber lasers; Laser modes; Lesions; Liver; Magnetic cores; Magnetic resonance imaging; Medical treatment; Optical pulses; Power lasers; Silicon compounds; Humans; Hyperthermia, Induced; Laser Therapy; Liver Neoplasms; Magnetic Resonance Imaging; Models, Biological; Predictive Value of Tests;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4352261

Filename

4352261