Fluorescence diffuse optical tomography: A simulation-based study comparing time-resolved and continuous wave reconstructions performances

Author

Ducros, Nicolas ; Silva, Anabela Da ; Dinten, Jean-Marc ; Peyrin, Francoise

Author_Institution

Micro Technol. for Biol. & Healthcare Div., CEA-LETI MINATEC, Grenoble

fYear

2008

fDate

14-17 May 2008

Firstpage

388

Lastpage

391

Abstract

The present paper is devoted to a comparison between time- resolved fluorescence diffuse optical tomography and continuous wave fluorescence diffuse optical tomography. Both of these techniques aim at reconstructing 3D biodistribution of fluorescent markers embedded in biological tissues. The study is restricted in the time domain to the exploitation of the first three temporal moments of measurements. The temporal benefits in terms of reconstruction have been shown to depend strongly on the optical parameters of the medium investigated as well as the fluorescence lifetime.

Keywords

biological tissues; biomedical optical imaging; fluorescence; image reconstruction; inverse problems; medical image processing; optical tomography; 3D fluorescent marker biodistribution; biological tissues; continuous wave optical tomography; fluorescence diffuse optical tomography; fluorescence lifetime; image reconstruction; time-resolved optical tomography; Biological tissues; Biomedical optical imaging; Distortion measurement; Fluorescence; Optical attenuators; Optical distortion; Optical imaging; Optical propagation; Optical scattering; Tomography; Fluorescence Diffuse Optical Tomography; Inverse Problems; Time-resolved imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on

Conference_Location

Paris

Print_ISBN

978-1-4244-2002-5

Electronic_ISBN

978-1-4244-2003-2

Type

conf

DOI

10.1109/ISBI.2008.4541014

Filename

4541014