Title :
Arrhythmogenesis Research: A Perspective from Computational Electrophysiology Viewpoint
Author :
Trayanova, N. ; Plank, G.
Author_Institution :
Johns Hopkins Univ., Baltimore
Abstract :
The mechanisms by which arrhythmias are generated in the heart remains a field of intensive research. Recent advances in computational biology and electrophysiology have enabled researchers to use an alternative tool in the study of arrhythmia mechanisms, the multi-scale modeling and simulation of cardiac arrhythmogenesis at the organ level. This article reviews the recent advances and achievements using this approach.
Keywords :
bioelectric potentials; electrocardiography; medical computing; arrhythmia mechanisms; cardiac arrhythmogenesis simulation; computational biology; electric current; electrophysiology; heart; multiscale modeling; Anisotropic magnetoresistance; Biological system modeling; Biomembranes; Cardiac tissue; Defibrillation; Electric shock; Extracellular; Heart; Myocardium; Optical fiber polarization; Arrhythmias; bidomain model; modeling; Animals; Arrhythmias, Cardiac; Cardiac Electrophysiology; Computational Biology; Heart; Humans; Imaging, Three-Dimensional; Models, Cardiovascular; Rabbits;
Conference_Titel :
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
Conference_Location :
Lyon
Print_ISBN :
978-1-4244-0787-3
DOI :
10.1109/IEMBS.2007.4352310
