Title :
Automated Cell Apoptosis Characterization using Active Contours
Author :
Doukas, C.N. ; Maglogiannis, I.
Author_Institution :
Univ. of the Aegean, Samos
Abstract :
Programmed cell death, also known as apoptosis, is of fundamental importance in many biological processes and also highly associated with serious diseases like cancer and HIV. The current paper presents an innovative method for apoptosis phenomenon characterization based on apoptotic cell quantification and detection using active contours (snakes). Evaluation results against manual counts have proved the high accuracy and efficiency of the developed method.
Keywords :
biomedical optical imaging; cancer; cellular biophysics; medical image processing; HIV; active contours; apoptotic cell detection; apoptotic cell quantification; automated cell apoptosis; cancer; programmed cell death; snakes; Active contours; Biomedical imaging; Cancer; Cells (biology); Chemicals; DNA; Data mining; Diseases; Human immunodeficiency virus; Microscopy; Animals; Apoptosis; Cells, Cultured; HIV Infections; Humans; Image Processing, Computer-Assisted; Microscopy, Video; Neoplasms; Software;
Conference_Titel :
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
Conference_Location :
Lyon
Print_ISBN :
978-1-4244-0787-3
DOI :
10.1109/IEMBS.2007.4352414