• DocumentCode
    1824511
  • Title

    Estimation of parameters in the linear-fractional models

  • Author

    Fang-Xiang Wu

  • Author_Institution
    Univ. of Saskatchewan, Saskatoon
  • fYear
    2007
  • fDate
    22-26 Aug. 2007
  • Firstpage
    1086
  • Lastpage
    1089
  • Abstract
    The linear-fractional model (LFM) is a fraction function whose numerator and denominator are linear in parameters. The LFM is a group of models nonlinear in parameters. The estimation methods for nonlinear models can be applied to the FLM. However, the parameters in an LFM can naturally be divided into two groups: those in the numerator and those in the denominator. When the parameters in the denominator are known, the standard least squares algorithm for the linear model can be used to estimate the parameters in the numerator. On the other hand, when parameters in the numerator are known, by a reciprocal transformation, the standard least squares algorithm for the linear model can again be used to estimate the parameters in the denominator. From this observation, we develop a recursive least-squares algorithm for estimation of parameters in the LFM when both groups has unknown parameters. The basic idea is to estimate the parameters in the numerators for a given initial parameters in the denominator using the standard least squares algorithm for the linear model, and then to estimate the parameters in the denominator with the previous estimates of parameters in the denominator using the standard least squares algorithm for the linear model when new data is available. The simulation results validated the convergence of the proposed algorithm and also showed the superior performance of the algorithm proposed over some existing algorithm.
  • Keywords
    least squares approximations; molecular biophysics; physiological models; recursive estimation; fraction function; linear-fractional models; molecular biological systems; reciprocal transformation; recursive least-squares algorithm; standard least squares algorithm; Convergence; Cost function; Least squares approximation; Least squares methods; Parameter estimation; Recursive estimation; Sensitivity analysis; Linear-fractional model (LFM); models nonlinear in parameters; parameter estimation; recursive least squares algorithm; Algorithms; Animals; Computer Simulation; Humans; Linear Models; Models, Biological; Nonlinear Dynamics; Reproducibility of Results; Sensitivity and Specificity;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
  • Conference_Location
    Lyon
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-0787-3
  • Type

    conf

  • DOI
    10.1109/IEMBS.2007.4352484
  • Filename
    4352484