VLSI multivariate phase synchronization epileptic seizure detector

Author

Abdelhalim, K. ; Smolyakov, V. ; Shulyzki, R. ; Aziz, J.N.Y. ; Serletis, D. ; Carlen, P.L. ; Genov, R.

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Toronto, Toronto, ON, Canada

fYear

2011

fDate

April 27 2011-May 1 2011

Firstpage

461

Lastpage

464

Abstract

A low-power VLSI seizure detector is presented. It combines a 256-channel analog neural recording chip and a low-power synthesized digital VLSI processor. The processor computes the bivariate phase synchronization on any two neural inputs from a set of 256 and their instantaneous magnitude. For experimentation with in vitro epilepsy models, a low-cost technique to implement on-chip gold microelectrodes was utilized. Results are shown using an in vitro low Mg²⁺ mouse epilepsy model and human EEG data.

Keywords

VLSI; electroencephalography; gold; medical disorders; medical signal detection; medical signal processing; microelectrodes; neurophysiology; synchronisation; Au; EEG; analog neural recording chip; bivariate phase synchronization; low-power VLSI epileptic seizure detector; low-power synthesized digital VLSI processor; on-chip gold microelectrodes; Computer architecture; Epilepsy; Hippocampus; In vitro; Mice; Synchronization; Very large scale integration;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Engineering (NER), 2011 5th International IEEE/EMBS Conference on

Conference_Location

Cancun

ISSN

1948-3546

Print_ISBN

978-1-4244-4140-2

Type

conf

DOI

10.1109/NER.2011.5910586

Filename

5910586