MicroPET performance in the presence of the third gamma

Author

Converse, Alexander K. ; Nye, Jonathon A. ; Barnhart, Todd E. ; Dick, David W. ; Avila-Rodriguez, Miguel A. ; Sundaresan, Ramya ; Dallas, Corinne B. ; Nickles, Robert J. ; Kalin, Ned H. ; Roberts, Andrew D.

Author_Institution

Keck Laboratory for Functional Brain Imaging, Wisconsin Univ., Madison, WI, USA

Volume

3

fYear

2003

fDate

19-25 Oct. 2003

Firstpage

1797

Abstract

Isotopes in routine use for positron emission tomography (PET) produce only a single pair of 511 keV annihilation photons. "Dirty" positron emitters, e.g. ¹²⁴I, that emit additional gammas are increasingly of interest. Performance of the Concorde microPET P4 small animal scanner was experimentally studied. Three phantoms were used to compare the pure positron emitter ¹⁸F to ¹²⁴I and the convenient proxies ⁷⁰As and ⁷²As. While the third gamma had only a small impact on images of a contrast/detail phantom, resolution of hot sources on cold background was noticably reduced in a "Derenzo" phantom. A "NEMA" phantom exhibited a 15% background due to the third gamma.

Keywords

arsenic; fluorine; gamma-ray detection; image resolution; iodine; medical image processing; phantoms; positron emission tomography; radioisotopes; ¹²⁴I; ¹⁸F; ⁷⁰As; ⁷²As; Concorde microPET P4 small animal scanner; Derenzo phantom; NEMA phantom; contrast/detail phantom; dirty positron emitters; hot source resolution; isotopes; positron emission tomography; third gamma; Animals; Chemistry; Gamma ray detection; Gamma ray detectors; Germanium; Imaging phantoms; Isotopes; Myocardium; Positron emission tomography; Single photon emission computed tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2003 IEEE

ISSN

1082-3654

Print_ISBN

0-7803-8257-9

Type

conf

DOI

10.1109/NSSMIC.2003.1352227

Filename

1352227