Title :
Assessment of ventricular-arterial coupling with a model-based sensor
Author :
Desaive, Thomas ; Lambermont, Bernard ; Ghuysen, Alexandre ; Kolh, Phillippe ; Morimont, P. ; Dauby, P.C. ; Starfinger, Christina ; Hann, Christopher E. ; Shaw, Geoffrey M. ; Chase, J. Geoffrey
Author_Institution :
Cardiovascular Res. Center, Univ. of Liege, Liege, Belgium
Abstract :
Estimation of ventricular contractility is clinically important in diagnosing cardiac dysfunction in the critically ill. However, experimental assessment of indexes of ventricular contractility, such as the end-systolic pressure-volume relationship requires a highly invasive maneuver. This research describes the use of a previously validated cardiovascular system (CVS) model and identification process to evaluate the right-ventricle contractility as well as the right ventricular arterial coupling in septic shock. The results show good agreement with the gold-standard experimental assessment (conductance catheter method), and offer the potential to develop a model-based sensor to monitor the coupling in clinical realtime.
Keywords :
blood flow measurement; blood vessels; cardiovascular system; catheters; diseases; flow sensors; haemorheology; patient diagnosis; patient monitoring; physiological models; pressure sensors; blood flow measurement; cardiac dysfunction diagnosis; cardiovascular system model; clinical real-time monitoring; conductance catheter method; end-systolic pressure-volume relationship; gold-standard experimental assessment; model-based sensor; septic shock; ventricular contractility estimation; ventricular-arterial coupling assessment; Cardiovascular; ICU; Intensive Care; Model; Sensor; sepsis; ventricular function;
Conference_Titel :
Control 2010, UKACC International Conference on
Conference_Location :
Coventry
Electronic_ISBN :
978-1-84600-038-6
DOI :
10.1049/ic.2010.0292
