Title :
Biological codes for stretch
Author :
Craelius, William
Author_Institution :
Dept. of Med., State Univ. of New York Health Center, Brooklyn, NY, USA
Abstract :
The molecular behavior of mechanically activated ionic channels is compared with the cellular behavior of stretch receptor neurons. Both systems have a pulse-code-modulated output and both can be modeled, to a degree, as leaky integrators. The model states that stretch, represented by m(t) along with a random function x(t ), is integrated by the closed 1 state of the channel. The interval between bursts is determined by threshold, T. Thus the channel transduces stretch through a closed state and encodes it through an open state
Keywords :
mechanoception; neurophysiology; physiological models; biological codes; bursts; cellular behavior; leaky integrators; mechanically activated ionic channels; molecular behavior; pulse-code-modulated output; random function; threshold; Biological information theory; Biological system modeling; Biomembranes; Engineering in medicine and biology; Frequency; Fungi; Neurons; Physiology; Pulse modulation; Transducers;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96245
