Title :
Biopsy needle as MRE driver for tumor detection
Author :
Zhao, X.G. ; Zheng, Y. ; Chan, Q.C.C. ; Yang, X.F. ; Li, G. ; Yang, E.S.
Author_Institution :
Univ. of Hong Kong, Hong Kong
Abstract :
Magnetic Resonance Elastography (MRE) is a phase contrast imaging technique to quantitatively measure the elasticity of tissues. Typically, an oscillating driver is placed on the surface to generate the shear waves. The depth penetration of the wave is limited by attenuation and the biopsy procedure has to be done separately. In this study, we use a biopsy needle as the driver to detect the 15% porcine gel inclusion in a 10% porcine gel phantom which simulates a tumor in tissues. We also perform the experiment with the biopsy needle for in-vivo tumor detection in rabbits. It is shown that the biopsy needle driver can accurately measure the stiffness and location of the tumor.
Keywords :
biomechanics; biomedical MRI; biomedical measurement; cancer; elastic waves; elasticity; needles; phantoms; tumours; attenuation procedure; biopsy needle; in-vivo rabbit tumor detection; magnetic resonance elastography driver; oscillating driver; phase contrast imaging technique; porcine gel inclusion detection; porcine gel phantom; shear wave generation; tissue elasticity measurement; wave penetration depth; Attenuation; Biopsy; Elasticity; Magnetic resonance; Magnetic resonance imaging; Needles; Neoplasms; Phase measurement; Surface waves; Tumors; Biopsy needle; MR Elastography; Stiffness; Animals; Biopsy; Biopsy, Needle; Elasticity; Equipment Design; Extremities; Female; Image Enhancement; Magnetic Resonance Imaging; Models, Statistical; Neoplasms; Phantoms, Imaging; Rabbits; Stress, Mechanical; Swine;
Conference_Titel :
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
Conference_Location :
Lyon
Print_ISBN :
978-1-4244-0787-3
DOI :
10.1109/IEMBS.2007.4352723