Title :
An impedance and multi-wavelength near-infrared spectroscopy IC for non-invasive blood glucose estimation
Author :
Kiseok Song ; Unsoo Ha ; Seongwook Park ; Hoi-Jun Yoo
Author_Institution :
Dept. of EE, KAIST, Daejeon, South Korea
Abstract :
A multi-modal spectroscopy IC combining the impedance spectroscopy (IMPS) and the multi-wavelength near-infrared spectroscopy (mNIRS) is proposed for high precision non-invasive glucose level estimation. A frequency sweep (10kHz - 76kHz) sinusoidal oscillator (FSSO) is proposed for high resolution (500 steps) for IMPS. The output voltage swing of the FSSO is stabilized by an adaptive gain control (AGC). The measurement results of the IMPS and mNIRS are combined by an artificial neural network (ANN) in external smart device so that mean absolute relative difference (mARD) is enhanced to 8.3% from 15% of IMPS, 15% - 20% of mNIRS. A proposed 12.5mm2 0.18μm CMOS chip consumes peak power of 38mW at 1.5V.
Keywords :
CMOS integrated circuits; biomedical electronics; biomedical measurement; blood vessels; infrared spectra; medical computing; neural chips; radiofrequency oscillators; sugar; AGC; ANN; CMOS chip; FSSO; IMPS; adaptive gain control; artificial neural network; external smart device; frequency sweep sinusoidal oscillator; high precision noninvasive glucose level estimation; impedance near-infrared spectroscopy IC; impedance spectroscopy; mARD; mNIRS; mean absolute relative difference; multimodal spectroscopy IC; multiwavelength near-infrared spectroscopy IC; output voltage swing; size 0.18 mum; voltage 1.5 V; Artificial neural networks; Estimation; Gain control; Integrated circuits; Resonant frequency; Spectroscopy; Sugar;
Conference_Titel :
VLSI Circuits Digest of Technical Papers, 2014 Symposium on
Conference_Location :
Honolulu, HI
Print_ISBN :
978-1-4799-3327-3
DOI :
10.1109/VLSIC.2014.6858407
