Title :
Impedance spectroscopy of Chicken Infectious Laryngotracheitis Virus Based on atomic force microscopy
Author :
Schulte, Michael B. ; Dong, Zhuxin ; Tung, Steve ; Kim, Jin-Woo ; Wejinya, Uche ; Moon, Hyung-Mo ; Kong, Byung-Whi
Author_Institution :
Dept. of Mech. Eng., Univ. of Arkansas, Fayetteville, AR, USA
Abstract :
The AC impedance spectroscopy of Chicken Infectious Laryngotracheitis Virus (ILTV, gallid herpesvirus 1) was measured using atomic force microscopy (AFM). The result indicates a 30% difference in the absolute impedance values between the control and virus samples within a 10-65 kHz frequency range. Using an equivalent circuit of the systems and an electrical curve fitting program, the data shows the average capacitance of a single virus particle is approximately 6 nF. Based on a similar analysis of the electrical properties of polystyrene beads, the overall dielectric constant of the ILTV was determined to be approximately 2.4.
Keywords :
atomic force microscopy; bioelectric phenomena; biomedical measurement; capacitance; electric impedance; electric impedance measurement; equivalent circuits; microorganisms; permittivity; polymers; AC impedance spectroscopy; ILTV; atomic force microscopy; chicken; dielectric constant; electrical curve fitting program; electrical properties; equivalent circuit; frequency 10 kHz to 65 kHz; gallid herpesvirus 1; infectious laryngotracheitis virus; polystyrene beads; Biology; Capacitance; Impedance; Impedance measurement; Indium tin oxide; Mechanical factors; Propagation losses; AC impedance spectroscopy; AFM; Dielectric constant; Equivelent cuircut; ILTV; Microelectro-mechanical systems (MEMS); Polystyrene bead; Total analysis system (TAS);
Conference_Titel :
Nano/Molecular Medicine and Engineering (NANOMED), 2009 IEEE International Conference on
Conference_Location :
Tainan
Print_ISBN :
978-1-4244-5528-7
DOI :
10.1109/NANOMED.2009.5559077
