Title :
Detection of Staphylococcus aureus using hydrothermally roughened substrates
Author :
Yang, Jung-Yen ; Chen, Yu ; Cheng, Hui-Wen ; Lin, Chi-Hung ; Li, Yiming
Author_Institution :
Nat. Nano Device Labs., Hsinchu, Taiwan
Abstract :
In this work, we fabricate a surface-enhanced Raman scattering (SERS)-active substrate with low background signals using bottom-up approach. Staphylococcus aureus has been used as Raman probe to evaluate its enhancement capability. The experimental results of this study show that Staphylococcus aureus was well resolved using gold-coated hydrothermally roughened TiO2 substrates.
Keywords :
Raman spectroscopy; biological techniques; microorganisms; surface enhanced Raman scattering; surface roughness; Au-TiO2; Raman probe; SERS; Staphylococcus aureus; TiO2; hydrothermal roughening; hydrothermally roughened substrates; surface-enhanced Raman scattering; Fingerprint recognition; Gold; Rough surfaces; Substrates; Surface roughness; Surface treatment; FDTD; Local Field; Maxwell´s equations; Raman spectroscopy; SERS-active substrate; Staphylococcus aureus; X-ray photoelectron spectroscopy (XPS); atomic force microscopy (AFM); confocal microscopic Raman spectrometer; contact angle (CA); hydrothermal treatment surface-enhanced Raman scattering (SERS); scanning electron microscope (SEM);
Conference_Titel :
Nano/Molecular Medicine and Engineering (NANOMED), 2009 IEEE International Conference on
Conference_Location :
Tainan
Print_ISBN :
978-1-4244-5528-7
DOI :
10.1109/NANOMED.2009.5559085
