Detection of Staphylococcus aureus using hydrothermally roughened substrates

Author

Yang, Jung-Yen ; Chen, Yu ; Cheng, Hui-Wen ; Lin, Chi-Hung ; Li, Yiming

Author_Institution

Nat. Nano Device Labs., Hsinchu, Taiwan

fYear

2009

fDate

18-21 Oct. 2009

Firstpage

210

Lastpage

214

Abstract

In this work, we fabricate a surface-enhanced Raman scattering (SERS)-active substrate with low background signals using bottom-up approach. Staphylococcus aureus has been used as Raman probe to evaluate its enhancement capability. The experimental results of this study show that Staphylococcus aureus was well resolved using gold-coated hydrothermally roughened TiO₂ substrates.

Keywords

Raman spectroscopy; biological techniques; microorganisms; surface enhanced Raman scattering; surface roughness; Au-TiO₂; Raman probe; SERS; Staphylococcus aureus; TiO₂; hydrothermal roughening; hydrothermally roughened substrates; surface-enhanced Raman scattering; Fingerprint recognition; Gold; Rough surfaces; Substrates; Surface roughness; Surface treatment; FDTD; Local Field; Maxwell´s equations; Raman spectroscopy; SERS-active substrate; Staphylococcus aureus; X-ray photoelectron spectroscopy (XPS); atomic force microscopy (AFM); confocal microscopic Raman spectrometer; contact angle (CA); hydrothermal treatment surface-enhanced Raman scattering (SERS); scanning electron microscope (SEM);

fLanguage

English

Publisher

ieee

Conference_Titel

Nano/Molecular Medicine and Engineering (NANOMED), 2009 IEEE International Conference on

Conference_Location

Tainan

Print_ISBN

978-1-4244-5528-7

Type

conf

DOI

10.1109/NANOMED.2009.5559085

Filename

5559085