Title :
A preliminary investigation on MEMS based immunosensor for E. coli O157:H7 detection
Author :
Bakar, M. H Abu ; Ibrahim, M.H. ; Kassim, N.M. ; Mohammad, A.B.
Author_Institution :
Photonics Technol. Centre, Univ. Teknol. Malaysia, Skudai, Malaysia
Abstract :
Bio-recognition layers on sensors can be designed in various ways; however the most popular approach is to immobilise antibodies for specific capture of analytes also known as immunosensor. This paper presents a preliminary study on MEMS based immunosensor for detecting Escherichia coli 0157:H7. In this paper, the recent progress within biosensors for E. coli O157:H7 detection will be reviewed. We will discuss the strengths and limitations of current sensor technologies for the detection of E. coli 0157:H7 .This paper explores the previous methods that have been employed to detect E. coli O157:H7 based on their detection scheme, detection limit, and response time. The reasons focusing on sensor utilizing specifically defined microcantilever using piezoresistive detection scheme is also discussed. We will also explain briefly on the theoretical aspects governing the relation between surface stress and the bending of the microcantilever.
Keywords :
bioMEMS; biosensors; cantilevers; microorganisms; Escherichia coli detection; MEMS immunosensor; analyte capture; antibody immobilisation; bending; biorecognition layers; biosensors; microcantilever; surface stress; Biosensors; Contamination; Immune system; Micromechanical devices; Microorganisms; Optical fiber sensors; Optical surface waves; Piezoresistance; Sensor phenomena and characterization; Water pollution; Biosensor; Escherichia coli; Immunosensor; MEMS; Microcantilever; O157:H7; Piezoresistive; Surface stress; antibodies; bacteria; detection;
Conference_Titel :
Communications (MICC), 2009 IEEE 9th Malaysia International Conference on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4244-5531-7
DOI :
10.1109/MICC.2009.5431414
