Live demonstration: A smart camera for real-time monitoring of fluorescent cell biomarkers

Author

Ghaye, J. ; Muldur, S.K. ; Urban, P. ; Kinsner-Ovaskainen, A. ; Colpo, P. ; Demarchi, D. ; De Micheli, G. ; Carrara, S.

Author_Institution

Integrated Syst. Lab., Ecole Polytech. Fed. de Lausanne, Lausanne, Switzerland

fYear

2014

fDate

22-24 Oct. 2014

Firstpage

169

Lastpage

169

Abstract

This live demonstration is centered around a field programmable gate array (FPGA) based image processing system, or smart camera, monitoring in real-time cell biomarkers. The system relies on the ability to monitor in-vitro different cell reactions via exogenous fluorescent markers, and extract quantitative metrics related to the monitored phenomenon. For the purpose of the live demonstration, the system is applied to the quantification of toll-like surface receptor 2 (TLR2), an inflammatory biomarker and to the quantification of the uptake of RubyPy-labeled silica nanoparticules.

Keywords

biomedical optical imaging; cameras; cellular biophysics; field programmable gate arrays; fluorescence; medical image processing; nanomedicine; nanoparticles; silicon compounds; FPGA based image processing system; RubyPy-labeled silica nanoparticule uptake; SiO₂; field programmable gate array; inflammatory biomarker monitoring; real-time fluorescent cell biomarker monitoring; smart camera; toll-like surface receptor 2 quantification; Biomarkers; Biomedical monitoring; Field programmable gate arrays; Microscopy; Monitoring; Nanobioscience; Smart cameras;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE

Conference_Location

Lausanne

Type

conf

DOI

10.1109/BioCAS.2014.6981672

Filename

6981672