• DocumentCode
    184550
  • Title

    Live demonstration: Automated design of artificial biological functions based on fuzzy logic

  • Author

    Gendrault, Y. ; Madec, M. ; Lemaire, M. ; Lallement, C. ; Haiech, J.

  • Author_Institution
    Lab. Icube, Univ. de Strasbourg, Strasbourg, France
  • fYear
    2014
  • fDate
    22-24 Oct. 2014
  • Firstpage
    189
  • Lastpage
    189
  • Abstract
    Currently, several levels of abstraction can be used to model targeted biological application and their associated assembly of elementary biological components (i.e.: BioBricks). The highest one uses the analogy between the behavior of biological mechanism and digital gates. The lowest one uses ordinary differential equations to get accurate and quantitative results. To bridge the gap between these two levels of abstraction, we developed models based on fuzzy logic. This live demonstration is divided in two parts: the first one will consist in the presentation of the algorithm we developed and its illustration on the modeling of different biological systems. The second one is focused on the integration of this algorithm in a complete design flow for synthetic biology. For that, we will present the automation tool that uses fuzzy logic models in order to pick out BioBricks from a database and choose the best assembly according to a given targeted biological function.
  • Keywords
    biological techniques; biology computing; differential equations; fuzzy control; physiological models; BioBricks; abstraction levels; artificial biological functions; associated assembly; automated design; automation tool; biological application; biological mechanism behavior; biological system modeling; complete design flow; digital gates; elementary biological components; fuzzy logic models; live demonstration; ordinary differential equations; synthetic biology; targeted biological function; Algorithm design and analysis; Assembly; Biological information theory; Biological system modeling; Fuzzy logic; Logic gates; Mathematical model;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE
  • Conference_Location
    Lausanne
  • Type

    conf

  • DOI
    10.1109/BioCAS.2014.6981692
  • Filename
    6981692