DocumentCode
184550
Title
Live demonstration: Automated design of artificial biological functions based on fuzzy logic
Author
Gendrault, Y. ; Madec, M. ; Lemaire, M. ; Lallement, C. ; Haiech, J.
Author_Institution
Lab. Icube, Univ. de Strasbourg, Strasbourg, France
fYear
2014
fDate
22-24 Oct. 2014
Firstpage
189
Lastpage
189
Abstract
Currently, several levels of abstraction can be used to model targeted biological application and their associated assembly of elementary biological components (i.e.: BioBricks). The highest one uses the analogy between the behavior of biological mechanism and digital gates. The lowest one uses ordinary differential equations to get accurate and quantitative results. To bridge the gap between these two levels of abstraction, we developed models based on fuzzy logic. This live demonstration is divided in two parts: the first one will consist in the presentation of the algorithm we developed and its illustration on the modeling of different biological systems. The second one is focused on the integration of this algorithm in a complete design flow for synthetic biology. For that, we will present the automation tool that uses fuzzy logic models in order to pick out BioBricks from a database and choose the best assembly according to a given targeted biological function.
Keywords
biological techniques; biology computing; differential equations; fuzzy control; physiological models; BioBricks; abstraction levels; artificial biological functions; associated assembly; automated design; automation tool; biological application; biological mechanism behavior; biological system modeling; complete design flow; digital gates; elementary biological components; fuzzy logic models; live demonstration; ordinary differential equations; synthetic biology; targeted biological function; Algorithm design and analysis; Assembly; Biological information theory; Biological system modeling; Fuzzy logic; Logic gates; Mathematical model;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE
Conference_Location
Lausanne
Type
conf
DOI
10.1109/BioCAS.2014.6981692
Filename
6981692
Link To Document