Live demonstration: An extended-gate CMOS sensor array with enzyme-immobilized microbeads for redox-potential glucose detection

Author

Komori, Hayato ; Niitsu, Kiichi ; Tanaka, J. ; Ishige, Yu ; Kamahori, Masao ; Nakazato, Kazuo

Author_Institution

Dept. of Electr. Eng. & Comput. Sci., Nagoya Univ., Nagoya, Japan

fYear

2014

fDate

22-24 Oct. 2014

Firstpage

191

Lastpage

191

Abstract

Glucose detection associated with CMOS-based electronics has great potential from the viewpoints of cost, form factor, and simplicity. There are two conventional approaches for emerging CMOS-based glucose detection. One is based on direct charge detection, and another is based on pH detection. Unfortunately, these methods are susceptible to buffer conditions such as the salt concentration and pH buffer capacity, which can seriously degrade their accuracy and reliability.

Keywords

CMOS integrated circuits; bioMEMS; biochemistry; biological techniques; biosensors; electric charge; electrochemical sensors; enzymes; microfluidics; molecular biophysics; oxidation; pH measurement; reduction (chemical); sensor arrays; sugar; CMOS-based electronics; CMOS-based glucose detection; buffer condition; direct charge detection; enzyme-immobilized microbead; extended-gate CMOS sensor array; glucose detection accuracy; glucose detection cost; glucose detection form factor; glucose detection reliability; glucose detection simplicity; live demonstration; pH buffer capacity; pH detection; redox; salt concentration; Arrays; Biochemistry; Biomedical measurement; CMOS integrated circuits; Electric potential; Power supplies; Sugar;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE

Conference_Location

Lausanne

Type

conf

DOI

10.1109/BioCAS.2014.6981694

Filename

6981694