Title :
Live demonstration: An extended-gate CMOS sensor array with enzyme-immobilized microbeads for redox-potential glucose detection
Author :
Komori, Hayato ; Niitsu, Kiichi ; Tanaka, J. ; Ishige, Yu ; Kamahori, Masao ; Nakazato, Kazuo
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Nagoya Univ., Nagoya, Japan
Abstract :
Glucose detection associated with CMOS-based electronics has great potential from the viewpoints of cost, form factor, and simplicity. There are two conventional approaches for emerging CMOS-based glucose detection. One is based on direct charge detection, and another is based on pH detection. Unfortunately, these methods are susceptible to buffer conditions such as the salt concentration and pH buffer capacity, which can seriously degrade their accuracy and reliability.
Keywords :
CMOS integrated circuits; bioMEMS; biochemistry; biological techniques; biosensors; electric charge; electrochemical sensors; enzymes; microfluidics; molecular biophysics; oxidation; pH measurement; reduction (chemical); sensor arrays; sugar; CMOS-based electronics; CMOS-based glucose detection; buffer condition; direct charge detection; enzyme-immobilized microbead; extended-gate CMOS sensor array; glucose detection accuracy; glucose detection cost; glucose detection form factor; glucose detection reliability; glucose detection simplicity; live demonstration; pH buffer capacity; pH detection; redox; salt concentration; Arrays; Biochemistry; Biomedical measurement; CMOS integrated circuits; Electric potential; Power supplies; Sugar;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE
Conference_Location :
Lausanne
DOI :
10.1109/BioCAS.2014.6981694
