Design considerations for high-density fully intraocular epiretinal prostheses

Retinal prostheses have successfully proven to be a viable treatment for advanced stages of retinal degenerative diseases such as retinitis pigmetosa. However, current implementations have critical limitations that affect their functionality and resolution. This paper reviews design challenges of the electronics considering the biology of the eye and discusses new approaches for future high-density fully intraocular prostheses. An origami retinal implant that has the potential to alleviate the size, power and cost constraints of such systems is proposed. Measured results of enabling technologies are also discussed.