Title :
An implantable optrode with Self-diagnostic function in 0.35µm CMOS for optical neural stimulation
Author :
Hubin Zhao ; Sokolov, Danil ; Degenaar, Patrick
Author_Institution :
Sch. of Electr. & Electron. Eng., Newcastle Univ., Newcastle upon Tyne, UK
Abstract :
One of the key challenges in the optogenetic field is to develop novel optical delivery devices that have the feasibility for implantable neural stimulation. In this paper, a CMOS-Gallium Nitride based optrode is proposed for neural stimulation with optogenetic methodology. The optrode base unit has been designed in a X-Fab 0.35um CMOS process and consists of control and sensing circuitry and six stimulation centres. Each centre has connection points for connecting three micro light emitting diodes (LEDs) to achieve local light delivery. In addition, we develop a self-diagnostic function to monitor working condition of LEDs in real time. This strategy highly improves the reliability and safety of the optrode for implantable applications.
Keywords :
CMOS image sensors; biomedical equipment; fibre optic sensors; light emitting diodes; neurophysiology; patient diagnosis; patient monitoring; prosthetics; CMOS-gallium nitride-based optrode; LED; X-Fab CMOS process; implantable applications; implantable neural stimulation; implantable optrode; local light delivery; microlight emitting diodes; optical delivery devices; optical neural stimulation; optogenetic field; optogenetic methodology; self-diagnostic function; size 0.35 mum; CMOS integrated circuits; Laser beam cutting; Light emitting diodes; Prosthetics; Retina; Silicon; Transistors;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE
Conference_Location :
Lausanne
DOI :
10.1109/BioCAS.2014.6981708
