Title :
Effect of stimulus pulsewidth on spatial selectivity of neural stimulation
Author :
Grill, Warren M. ; Mortimer, J. Thomas
Author_Institution :
Appl. Neural Control Lab., Case Western Reserve Univ., Cleveland, OH, USA
Abstract :
The objective of this study was to determine the effect of stimulus pulsewidth (PW) on selective activation of peripheral nerve fibers. Computer simulations using a cable model of a mammalian myelinated nerve fiber indicated that shorter PWs increased the difference between the threshold currents of fibers lying at different distances from an electrode. Experiments conducted in a cat model revealed that shorter PWs generated larger torques before spillover, and created a larger range of currents over which the torque was a monotonically increasing function of the stimulus current amplitude. Thus, shorter PWs allowed more spatially selective stimulation of nerve fibers
Keywords :
bioelectric phenomena; muscle; neurophysiology; physiological models; cable model; cat model; computer simulations; currents; mammalian myelinated nerve fiber; motor neurons; neural stimulation; peripheral nerve fibers; selective activation; spatial selectivity; spatially selective stimulation; spillover; stimulus current amplitude; stimulus pulsewidth; threshold currents; torque; Biomedical engineering; Computer simulation; Electrodes; Muscles; Nerve fibers; Neurons; Optical fiber cables; Recruitment; Space vector pulse width modulation; Threshold current; Torque;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.412003