Effect of stimulus pulsewidth on spatial selectivity of neural stimulation

Author

Grill, Warren M. ; Mortimer, J. Thomas

Author_Institution

Appl. Neural Control Lab., Case Western Reserve Univ., Cleveland, OH, USA

fYear

1994

fDate

3-6 Nov 1994

Firstpage

363

Abstract

The objective of this study was to determine the effect of stimulus pulsewidth (PW) on selective activation of peripheral nerve fibers. Computer simulations using a cable model of a mammalian myelinated nerve fiber indicated that shorter PWs increased the difference between the threshold currents of fibers lying at different distances from an electrode. Experiments conducted in a cat model revealed that shorter PWs generated larger torques before spillover, and created a larger range of currents over which the torque was a monotonically increasing function of the stimulus current amplitude. Thus, shorter PWs allowed more spatially selective stimulation of nerve fibers

Keywords

bioelectric phenomena; muscle; neurophysiology; physiological models; cable model; cat model; computer simulations; currents; mammalian myelinated nerve fiber; motor neurons; neural stimulation; peripheral nerve fibers; selective activation; spatial selectivity; spatially selective stimulation; spillover; stimulus current amplitude; stimulus pulsewidth; threshold currents; torque; Biomedical engineering; Computer simulation; Electrodes; Muscles; Nerve fibers; Neurons; Optical fiber cables; Recruitment; Space vector pulse width modulation; Threshold current; Torque;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE

Conference_Location

Baltimore, MD

Print_ISBN

0-7803-2050-6

Type

conf

DOI

10.1109/IEMBS.1994.412003

Filename

412003