Title :
Transcranial magnetic induced motor evoked potentials in primates: the technique and anesthetic effects
Author :
Ghaly, Ramsis F. ; Stone, James L. ; Aldrete, J. Antonio ; Kartha, Radha K.
Author_Institution :
Cook County Hospital, Chicago, IL, USA
Abstract :
The use of transcranial magnetic stimulation (TMS) to produce motor evoked potentials (MEPs) was examined in primates anesthetized with different anesthetic agents including nitrous oxide, thiamylal sodium, and ketamine. Reproducible upper and lower limb MEP responses were recorded in all animals following TMS using an average mean field of 0.75-0.9 T. Nitrous oxide and ketamine maintained the MEP responses, whereas thiamylal abolished them. The technique is reportedly safe, simple, and efficacious in the primate model
Keywords :
bioelectric potentials; biological techniques and instruments; biomagnetism; 0.75 to 0.9 T; N2O; anesthetic effects; animals; ketamine; lower limb; primates; thiamylal Na; transcranial magnetic induced motor evoked potentials; upper limb; Analysis of variance; Anesthetic drugs; Animals; Coils; Delay; Electromyography; Magnetic fields; Magnetic stimulation; Muscles; Surgery;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96347
