Title :
The effect of pulsed electrical fields on biological cells
Author :
Schoenbach, K.H. ; Abou-Ghazala, A. ; Vithoulkas, T. ; Alden, R.W. ; Turner, Richard ; Beebe, S.
Author_Institution :
Phys. Electron. Res. Inst., Old Dominion Univ., Norfolk, VA, USA
fDate :
June 29 1997-July 2 1997
Abstract :
Experimental studies on the effect of pulsed electric fields on aquatic organisms and on cancer cells have shown that the stress level of micro- and macro-organisms can be controlled by varying the pulse amplitude and pulse duration. It could also be shown that an increase in frequency, or reduction in pulse duration, respectively, causes the location of the cell damage to change from the outer membrane to the nucleus. The experimental results can be explained by considering the equivalent circuit of biological cells.
Keywords :
biological effects of fields; aquatic organisms; biological cells; cancer cells; cell damage location; equivalent circuit; frequency increase; macroorganisms; microorganisms; nucleus; outer membrane; pulse amplitude variation; pulse duration reduction; pulse duration variation; pulsed electric fields; stress level; Biological cells; Biomembranes; Breakdown voltage; Cancer; Cells (biology); Dielectrics; Electric breakdown; Equivalent circuits; Organisms; Stress;
Conference_Titel :
Pulsed Power Conference, 1997. Digest of Technical Papers. 1997 11th IEEE International
Conference_Location :
Baltimore, MA, USA
Print_ISBN :
0-7803-4213-5
DOI :
10.1109/PPC.1997.679279
