Lateral-driven continuous magnetophoretic microseparator for separating blood cells based on their native magnetic properties

We present a lateral-driven continuous magnetophoretic separator for separating red and white blood cells from peripheral whole blood, based on their native magnetic properties. The separation is achieved using a highgradient magnetic field, caused by a ferromagnetic wire array inlaid on glass substrate. The wire array creates an even lateral magnetophoretic force on the whole area of the microchannel, improving the separation efficiency and throughput. When the flow rate and external magnetic flux were 20 mul/h and 0.3 T, respectively, the microseparator continuously separated out 93.9% of red blood cells (RBCs) and 89.2% of white blood cells (WBCs) from peripheral whole blood.