Digital holographic microscopy applied to life sciences

Author

Depeursinge, C. ; Colomb, T. ; Emery, Y. ; Kuhn, J. ; Charriere, F. ; Rappaz, B. ; Marquet, P.

Author_Institution

Ecole Polytech. Fed. de Lausanne, Lausanne

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

6243

Lastpage

6246

Abstract

Digital holographic microscopy (DHM) is applied to life sciences applications and demonstrate its capability of real-time imaging and quantitative measurements of physiological parameters such as cell volume or mean cell hemoglobin concentration (MCHC) of erythrocyte cells. DHM has the advantage to be non-invasive (no phototoxicity, no contrast agents) and allows a high throughput measurements.

Keywords

cellular biophysics; holography; medical image processing; molecular biophysics; cell volume; digital holographic microscopy; erythrocyte cells; life sciences; mean cell hemoglobin concentration; real time imaging; Biomedical optical imaging; Charge coupled devices; Charge-coupled image sensors; Holographic optical components; Holography; Optical imaging; Optical interferometry; Optical microscopy; Optical refraction; Optical sensors; Biological Science Disciplines; Holography; Microscopy; Signal Processing, Computer-Assisted; Technology Assessment, Biomedical;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4353782

Filename

4353782