Title :
A high efficiency micromachined artificial lung
Author :
Potkay, Joseph A.
Author_Institution :
Dept. of Veterans Affairs Med. Center, Adv. Platform Technol. Center (APT Center), Cleveland, OH, USA
Abstract :
This paper presents the design, fabrication and first results for a microfabricated artificial lung with feature sizes that are comparable to that of the natural lung. The device is targeted at an increased gas transfer efficiency and portability compared to its current commercial alternatives and boasts the thinnest silicone gas transfer membrane and the lowest membrane diffusional resistance for a silicone-based device to date. Devices with 15 mum-thick membranes and 30 mum-tall channels achieved membrane and blood-side diffusional resistances of 27 times 103 and 118 times 103 ml-1middotsmiddotcm2middotcmHg, respectively, for oxygen.
Keywords :
artificial organs; bioMEMS; biodiffusion; biomembranes; microfabrication; silicones; SiO2; artificial lung microfabrication; membrane diffusional resistance; micromachined device fabrication; silicone gas transfer membrane; silicone-based device design; size 15 mum; size 30 mum; Biomembranes; Blood; Carbon dioxide; Diseases; Exchange rates; Fabrication; Humans; Immune system; Lungs; Surface resistance; Artificial lung; Micro-molding; Microfabrication; PDMS; Silicone; blood oxygenator; diffusion membrane;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International
Conference_Location :
Denver, CO
Print_ISBN :
978-1-4244-4190-7
Electronic_ISBN :
978-1-4244-4193-8
DOI :
10.1109/SENSOR.2009.5285592
