Title :
Nano monorail for molecular motors: Individually manipulated microtubules for kinesin motion
Author :
Tarhan, M.C. ; Jalabert, L. ; Yokokawa, R. ; Bottier, C. ; Collard, D. ; Fujita, H.
Author_Institution :
IIS, Univ. of Tokyo, Tokyo, Japan
Abstract :
In a motor protein system (kinesin/microtubule), individual microtubules were captured and relocated to build a complex nano-scale transport system. Micro tweezers, attached to a micromanipulator arm, were used to capture polarity marked microtubules. Precise relocation of those microtubules provided an oriented track along which kinesin-coated beads move according to the microtubule polarities.
Keywords :
bioMEMS; biological techniques; micromanipulators; molecular biophysics; nanoelectromechanical devices; proteins; complex nano-scale transport system; kinesin motion; micro tweezers; micromanipulator arm; microtubules; motor protein system; nano monorail; polarity; Coatings; Microfluidics; Micromanipulators; Micromotors; Nanobioscience; Phase locked loops; Polymers; Proteins; Rails; Transportation; Direct Transportation; Kinesin; Microtubules; Single Molecule Manipulation;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International
Conference_Location :
Denver, CO
Print_ISBN :
978-1-4244-4190-7
Electronic_ISBN :
978-1-4244-4193-8
DOI :
10.1109/SENSOR.2009.5285605
