Title :
Rapid elongation of a myelinated nerve fiber: a model for neural injury
Author :
Saatman, Kathyn E. ; Thibault, Lawrence E.
Author_Institution :
Dept. of Bioeng., Pennsylvania Univ., Philadelphia, PA, USA
Abstract :
A single nerve fiber from the sciatic nerve of a frog is presented as an isolated tissue model for neural trauma. An experimental system that delivers a controlled high-strain-rate uniaxial displacement pulse to the single fiber is described. The use of the system to study the effects of rapid stretch on the nodal regions of a myelinated nerve is discussed
Keywords :
biological techniques and instruments; biomechanics; neurophysiology; controlled high-strain-rate uniaxial displacement pulse; experimental system; frog sciatic nerve; isolated tissue model; myelinated nerve fiber; nerve nodal regions; neural injury model; neural trauma; rapid neural elongation; rapid sketch effects; Biomedical engineering; Biomembranes; Calcium; Capacitive sensors; Coils; Injuries; Microelectrodes; Nerve fibers; Pulleys; Uniaxial strain;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96394
