Comprehensive electrochemical imaging with local redox cycling-based electrochemical chip device for evaluation of three-dimensional culture cells

In this study, we have developed a novel electrochemical detection system containing many electrochemical sensors. The detection system is based on local redox cycling to incorporate many electrochemical sensors into small chip device. The density of the electrochemical sensors is the highest in the field of the electrochemical lab-on-a-chip devices. By using the chip device, comprehensive electrochemical imaging can be achieved. In this study, the chip device was applied for cell analysis of three-dimensional culture cells.