• DocumentCode
    1860016
  • Title

    Biomechanical properties of red blood cell through the motion inside a micro-channel

  • Author

    Tsai, Chia-Hung Dylan ; Kaneko, Makoto ; Sakuma, Shinya ; Arai, Fumihito

  • Author_Institution
    Dept. of Mech. Eng., Osaka Univ., Suita, Japan
  • fYear
    2012
  • fDate
    4-7 Nov. 2012
  • Firstpage
    390
  • Lastpage
    392
  • Abstract
    The behavior of red blood cell passing through a micro-channel can be divided into two phases, where one is the transition phase and the other is the steady-state phase. This paper focuses on the in-depth understanding of the transition phase from the viewpoint of the physical significance. By using the customized threshold for classifying two phases on the red blood cells from different subjects, we show that the deformation of the cells plays a critical role in the location of the transition point. The technique of locating the transition point is improved by analyzing the evolution of R2 value, which is used for locating the linear portion of motion profile. The experimental results are presented for supporting the proposed methods.
  • Keywords
    biomechanics; blood; cellular transport; deformation; microchannel flow; biomechanical properties; cell deformation; customized threshold; micro-channel; motion profile; red blood cell; steady-state phase; transition phase; transition point location;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro-NanoMechatronics and Human Science (MHS), 2012 International Symposium on
  • Conference_Location
    Nagoya
  • Print_ISBN
    978-1-4673-4811-9
  • Type

    conf

  • DOI
    10.1109/MHS.2012.6492475
  • Filename
    6492475