Title :
Liquid recirculation in microfluidic channels by the interplay of capillary and centrifugal forces
Author :
García-Cordero, J.L. ; Basabe-Desmonts, L. ; Ducrée, J. ; Lee, L.P. ; Ricco, A.J.
Author_Institution :
Biomed. Diagnostics Inst., Dublin City Univ., Dublin, Ireland
Abstract :
We demonstrate a technique to recirculate liquids in a microfluidic device, maintaining a thin fluid layer such that typical diffusion times for analytes to reach the device surface are < 1 min. Fluids can be recirculated at least 1000 times across the same surface region, with no change other than slight evaporation, by alternating the predominance of centrifugal and capillary forces. Mounted on a rotational platform, the device consists of two hydrophilic layers separated by a thin pressure-sensitive adhesive (PSA) layer that defines the microfluidic structure. We demonstrate rapid, effective fluid mixing with this device.
Keywords :
microchannel flow; mixing; capillary forces; centrifugal forces; liquid recirculation; microfluidic channels; pressure-sensitive adhesive layer; thin fluid layer; Biomedical engineering; Drives; Fabrication; Immune system; Liquids; Microfluidics; Polymers; Prototypes; Pumps; Surface contamination; Recirculation; capillary forces; centrifugal microfluidics; mixing; rare cell capture;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International
Conference_Location :
Denver, CO
Print_ISBN :
978-1-4244-4190-7
Electronic_ISBN :
978-1-4244-4193-8
DOI :
10.1109/SENSOR.2009.5285860
