• DocumentCode
    1870037
  • Title

    Microtubule sortiing within a given electric field by designing flexural rigidity

  • Author

    Isozaki, Naoto ; Shintaku, Hirofumi ; Kotera, Hidetoshi ; Meyhofer, Edgar ; Yokokawa, Ryuji

  • Author_Institution
    Kyoto Univ., Kyoto, Japan
  • fYear
    2015
  • fDate
    18-22 Jan. 2015
  • Firstpage
    238
  • Lastpage
    241
  • Abstract
    We propose a method to control gliding directions of kinesin-propelled microtubules (MTs) corresponding to their flexural rigidity (EI). We prepared two kinds of MTs having different EI and their trajectories within an electric field were clearly separated. Therefore, this study demonstrated the EI-altered MTs can be workhorses to sort/concentrate various combinations of target molecules loaded on MTs.
  • Keywords
    bioMEMS; biocontrol; electric fields; proteins; shear modulus; electric field; flexural rigidity; gliding direction control; kinesin-propelled microtubules; microtubule sorting; Electric fields; Equations; Mathematical model; Proteins; Reservoirs; Substrates; Trajectory;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro Electro Mechanical Systems (MEMS), 2015 28th IEEE International Conference on
  • Conference_Location
    Estoril
  • Type

    conf

  • DOI
    10.1109/MEMSYS.2015.7050932
  • Filename
    7050932
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1870037