Title :
Cell Adhesions on Nanoturf Surfaces
Author :
Choi, Chang-Hwan ; Hagvall, Sepideh H. ; Dunn, James C Y ; Wu, Benjamin M. ; Kim, Chang-Jin
Author_Institution :
Mechanical & Aerospace Engineering Dept., University of California at Los Angeles (UCLA), USA
Abstract :
We report on various aspects of cell adhesion of fibrolasts over densely-populated sharp-tip nano-post structures, which we term “ NanoTurf”. The ability to control the size, shape, and aspect ratio of the nanostructures enabled the study on the effect of surface three-dimensionality of the cell-matrix adhesion in detail. To our best knowledge, this is the first systematic investigation of the nanometric three-dimensional surface topography effect on cell adhesions.
Keywords :
Adhesives; Atomic force microscopy; Fibroblasts; Interference; Lithography; Nanostructures; Shape control; Silicon; Surface morphology; Surface topography;
Conference_Titel :
Micro Electro Mechanical Systems, 2006. MEMS 2006 Istanbul. 19th IEEE International Conference on
Conference_Location :
Istanbul, Turkey
Print_ISBN :
0-7803-9475-5
DOI :
10.1109/MEMSYS.2006.1627821
