DocumentCode
1877726
Title
Infrared Light Induced Patterning of Proteins on ppNIPAM Thermoresponsive Thin Films: A “ Protein Laser Printer ”
Author
Bohringer, K.F. ; Bilge, H. ; Xuanhong Cheng ; Ratner, B. ; Takeuchi, S. ; Fujita, H.
Author_Institution
Department of Electrical Engineering, University of Washington, Seattle, WA, USA; Institute of Industrial Science, University of Tokyo, Komaba, Tokyo, JAPAN
fYear
2006
fDate
22-26 Jan. 2006
Firstpage
530
Lastpage
533
Abstract
Controlled adsorption and patterning of proteins on a thin film of thermo-responsive plasma-deposited poly-N-isopropylacrylamide occurs in response to heating with a computer-controlled infrared laser beam, with pattern resolution in the single micrometer range and adsorption times within a few seconds. Deposition of multiple proteins in the same substrate region has been accomplished. Successful streptavidin-biotin and antibody-antigen binding indicates that protein function stays intact after proteins adsorb to the ppNIPAM bio-polymer surface.
Keywords
Infrared heating; Laser beams; Optical computing; Optical control; Particle beams; Plasmas; Proteins; Substrates; Temperature control; Transistors;
fLanguage
English
Publisher
ieee
Conference_Titel
Micro Electro Mechanical Systems, 2006. MEMS 2006 Istanbul. 19th IEEE International Conference on
Conference_Location
Istanbul, Turkey
ISSN
1084-6999
Print_ISBN
0-7803-9475-5
Type
conf
DOI
10.1109/MEMSYS.2006.1627853
Filename
1627853
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