The Mouse HRV Analysis Based on Radius of FOD

Environment change induces a great influence on mouse heartbeat. The Poincare plot and the first-order differential (FOD) plot are usually introduced to analyze heart rate variability (HRV), while both of them are qualitative methods to the research object. A quantitative approach is suggested to analyze abnormal HRV based on the FOD radius in this paper. Based on FOD sequence between the RR intervals, we get the FOD plot. FOD radius is estimated which divide FOD plot into two different regions: normal and abnormal region. So we get the information containing classification of RR intervals. Our research results show that, Concentrated Ambient Particles (CAPs) have significant adverse health effects on both healthy and unhealthy mice, and it´s much more sensitive to unhealthy mice.