• DocumentCode
    1881819
  • Title

    Graphical interface for gene network inference application

  • Author

    Zainudin, Suhaila ; Wei, Sim Kah ; Deris, Safaai

  • Author_Institution
    Fac. of Inf. Sci. & Technol., Univ. Kebangsaan Malaysia, Bangi, Malaysia
  • Volume
    1
  • fYear
    2010
  • fDate
    15-17 June 2010
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    A gene network shows the interactions between genes. Previous research has successfully infer gene network from microarray gene expression data using techniques from diverse fields such as pattern detection, machine learning and data mining. In this research, we applied the statistical language R for gene network inference. R provides statistical language and programming environment for statistical computing and graphics. We observed that R only provides command line interface with basic comand buttons. Hence, we built a gene network inference application with Microsoft Visual C# as the visual front-end and R as the back-end for novice R users who are interested to use our gene network inference tool. Th application has tabs which represents each phase of our inference methodology. Each time a user select and click, the command will be executed through the visual interface. Therefore, users no longer need to use the command line. The inference of gene network from gene expression data is useful for predicting relationships between genes. Gene network inference is important because it enhances the understanding on genomic function and directly helps development in bioinformatics and medical field.
  • Keywords
    bioinformatics; data mining; genomics; graphical user interfaces; learning (artificial intelligence); pattern recognition; statistical analysis; visual programming; Microsoft Visual C#; bioinformatics; data mining; gene network inference application; genomic function; graphical interface; machine learning; microarray gene expression; pattern detection; statistical computing; statistical language; Bioinformatics; Data visualization; Gene expression; Genomics; Proteins; Visualization; Gene network; inference; microarray;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information Technology (ITSim), 2010 International Symposium in
  • Conference_Location
    Kuala Lumpur
  • ISSN
    2155-897
  • Print_ISBN
    978-1-4244-6715-0
  • Type

    conf

  • DOI
    10.1109/ITSIM.2010.5561435
  • Filename
    5561435