Title :
A multichannel DNA SoC for rapid point-of-care gene detection
Author :
Garner, D.M. ; Hua Bai ; Georgiou, Pantelis ; Constandinou, Timothy G. ; Reed, S. ; Shepherd, L.M. ; Wong, Wing Kee ; Lim, K.T. ; Toumazou, Christofer
Author_Institution :
DNA Electron., London, UK
Abstract :
An all-electrical approach for fast genetic testing is developed. The system employs a custom SoC fabricated in unmodified CMOS, which is embedded in a microfluidic cartridge together with proprietary biochemistry and delivers a result within 3 minutes. The system is fully scalable, allowing multiple genetic letters to be identified.
Keywords :
CMOS integrated circuits; DNA; bioMEMS; biomedical measurement; biosensors; genetics; microfluidics; molecular biophysics; patient diagnosis; system-on-chip; fast genetic testing; microfluidic cartridge; multichannel DNA SoC; point of care gene detection; rapid gene detection; unmodified CMOS; Biomedical optical imaging; DNA; Electrodes; FETs; Genetics; Optical sensors; Probes; Sequences; Tagging; Temperature sensors;
Conference_Titel :
Solid-State Circuits Conference Digest of Technical Papers (ISSCC), 2010 IEEE International
Conference_Location :
San Francisco, CA
Print_ISBN :
978-1-4244-6033-5
DOI :
10.1109/ISSCC.2010.5433834
