Title :
Pain control on demand based on pulsed radio-frequency stimulation of the dorsal root ganglion using a batteryless implantable CMOS SoC
Author :
Chii-Wann Lin ; Hung-Wei Chiu ; Mu-Lien Lin ; Chi-Heng Chang ; I-Hsiu Ho ; Po Hsiang Fang ; Yi Chin Li ; Chang Lun Wang ; Yao-Chuan Tsai ; Yeong-Ray Wen ; Win-Pin Shih ; Yao-Joe Yang ; Shey-Shi Lu
Author_Institution :
Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
Electrical stimulation can effectively control or reduce the sensation of pain. This paper presents the implementation of a batteryless CMOS SoC with low-voltage pulsed radio-frequency (PRF) stimulation. Its effectiveness is demonstrated by observing the behavior of rats receiving localized bi-polar stimulus to the dorsal root ganglion (DRG) of the lumbar nerve without thermal damage.
Keywords :
CMOS integrated circuits; bioelectric phenomena; biomedical electronics; neurophysiology; prosthetics; system-on-chip; batteryless implantable CMOS SoC; dorsal root ganglion; electrical stimulation; frequency 1 MHz; localized bipolar stimulus; lumbar nerve; pain control on demand; pain sensation; pulsed radiofrequency stimulation; thermal damage; voltage 1.4 V to 3.3 V; Animals; Circuits; Clocks; Coils; Pain; Radio control; Radio frequency; Rats; Surgery; Voltage;
Conference_Titel :
Solid-State Circuits Conference Digest of Technical Papers (ISSCC), 2010 IEEE International
Conference_Location :
San Francisco, CA
Print_ISBN :
978-1-4244-6033-5
DOI :
10.1109/ISSCC.2010.5433936
