• DocumentCode
    1889271
  • Title

    A CMOS electrochemical impedance spectroscopy biosensor array for label-free biomolecular detection

  • Author

    Manickam, Arun ; Chevalier, Amelie ; McDermott, Maxwell ; Ellington, Andrew D ; Hassibi, Arjang

  • Author_Institution
    Univ. of Texas, Austin, TX, USA
  • fYear
    2010
  • fDate
    7-11 Feb. 2010
  • Firstpage
    130
  • Lastpage
    131
  • Abstract
    A fully integrated 10×10 electrochemical impedance spectroscopy array is designed for label-free biomolecular detection applications. Each biosensor pixel includes an on-chip bio-functionalized electrode and a direct-conversion receiver capable of measuring complex admittance levels as low as 10·¿¿-1 with a dynamic range larger than 90 dB in a 10 Hz-to-50 MHz frequency range.
  • Keywords
    CMOS integrated circuits; DNA; biosensors; electrochemical impedance spectroscopy; electrodes; molecular biophysics; proteins; receivers; sensor arrays; CMOS electrochemical impedance spectroscopy biosensor array; biosensor pixel; complex admittance levels; direct-conversion receiver; frequency 10 Hz to 50 MHz; label-free biomolecular detection applications; on-chip bio-functionalized electrode; Biosensors; DNA; Detectors; Electrochemical impedance spectroscopy; Electrodes; Frequency measurement; Gold; Magnetic analysis; Proteins; Signal to noise ratio;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Solid-State Circuits Conference Digest of Technical Papers (ISSCC), 2010 IEEE International
  • Conference_Location
    San Francisco, CA
  • ISSN
    0193-6530
  • Print_ISBN
    978-1-4244-6033-5
  • Type

    conf

  • DOI
    10.1109/ISSCC.2010.5434019
  • Filename
    5434019