Title :
Resonant based microwave biosensor for biological cells discrimination
Author :
Grenier, Katia ; Dubuc, David ; Poleni, Paul-Emile ; Kumemura, Momoko ; Toshiyoshi, Hiroshi ; Fujii, Teruo ; Fujita, Hiroyuki
Author_Institution :
LIMMS/CNRS-IIS, Univ. de Toulouse, Toulouse, France
Abstract :
This publication deals with a resonant RF-based biosensor for in-liquid operation. Stop-band filter modeling and characterizations are investigated in order to discriminate dead and alive suspensions of human cultured cells. This proof of concept demonstrator features noticeable contrasts on both resonant frequency (7%) and amplitude (2.1 dB). Theses results consequently demonstrate that RF detection can provide a non invasive sensing technique, which is compatible with a lab-on-a-chip approach to discriminate the pathological state of cells.
Keywords :
biosensors; cellular biophysics; lab-on-a-chip; microfluidics; physiological models; radiofrequency filters; biological cells discrimination; lab-on-a-chip; microfluidic channel; microwave biosensor; resonant amplitude; resonant frequency; stop-band filter modeling; Biological cells; Biological system modeling; Biosensors; Cells (biology); Humans; Microwave filters; Radio frequency; Resonance; Resonant frequency; Suspensions; Resonators; biology; filters; micro-fluidic; microwave; sensor;
Conference_Titel :
Radio and Wireless Symposium (RWS), 2010 IEEE
Conference_Location :
New Orleans, LA
Print_ISBN :
978-1-4244-4725-1
Electronic_ISBN :
978-1-4244-4726-8
DOI :
10.1109/RWS.2010.5434223
