Resonant based microwave biosensor for biological cells discrimination

Author

Grenier, Katia ; Dubuc, David ; Poleni, Paul-Emile ; Kumemura, Momoko ; Toshiyoshi, Hiroshi ; Fujii, Teruo ; Fujita, Hiroyuki

Author_Institution

LIMMS/CNRS-IIS, Univ. de Toulouse, Toulouse, France

fYear

2010

fDate

10-14 Jan. 2010

Firstpage

523

Lastpage

526

Abstract

This publication deals with a resonant RF-based biosensor for in-liquid operation. Stop-band filter modeling and characterizations are investigated in order to discriminate dead and alive suspensions of human cultured cells. This proof of concept demonstrator features noticeable contrasts on both resonant frequency (7%) and amplitude (2.1 dB). Theses results consequently demonstrate that RF detection can provide a non invasive sensing technique, which is compatible with a lab-on-a-chip approach to discriminate the pathological state of cells.

Keywords

biosensors; cellular biophysics; lab-on-a-chip; microfluidics; physiological models; radiofrequency filters; biological cells discrimination; lab-on-a-chip; microfluidic channel; microwave biosensor; resonant amplitude; resonant frequency; stop-band filter modeling; Biological cells; Biological system modeling; Biosensors; Cells (biology); Humans; Microwave filters; Radio frequency; Resonance; Resonant frequency; Suspensions; Resonators; biology; filters; micro-fluidic; microwave; sensor;

fLanguage

English

Publisher

ieee

Conference_Titel

Radio and Wireless Symposium (RWS), 2010 IEEE

Conference_Location

New Orleans, LA

Print_ISBN

978-1-4244-4725-1

Electronic_ISBN

978-1-4244-4726-8

Type

conf

DOI

10.1109/RWS.2010.5434223

Filename

5434223