• DocumentCode
    189696
  • Title

    Real-time gene newtorks control in microfluidics

  • Author

    Menolascina, Filippo

  • Author_Institution
    Dept. of Civil & Environ. Eng., Massachusetts Inst. of Technol., Cambridge, MA, USA
  • fYear
    2014
  • fDate
    24-27 June 2014
  • Firstpage
    1187
  • Lastpage
    1192
  • Abstract
    This tutorial paper presents two examples of invivo real-time control of gene regulatory networks in the eukaryote S. cerevisiae (baker´s yeast). I discuss the theoretical and experimental challenges this problem poses and describe a microfluidics-based platform to address them. The results obtained using this setup demonstrate the proposed approach is both feasible and capable of achieving superior performances.
  • Keywords
    biocontrol; microfluidics; networked control systems; real-time systems; baker yeast; eukaryote S. cerevisiae; gene regulatory networks; microfluidics; microfluidics-based platform; real-time gene network control; Biological system modeling; Control systems; Integrated circuit modeling; Mathematical model; Proteins; Real-time systems; Sugar;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Control Conference (ECC), 2014 European
  • Conference_Location
    Strasbourg
  • Print_ISBN
    978-3-9524269-1-3
  • Type

    conf

  • DOI
    10.1109/ECC.2014.6862646
  • Filename
    6862646