Broad-band Mach-Zehnder Interferometry as a detection principle for label-free biochemical sensing

Author

Kitsara, M. ; Raptis, I. ; Misiakos, K. ; Makarona, E.

Author_Institution

Inst. of Microelectron, NCSR "Demokritos", Aghia Paraskevi

fYear

2008

fDate

26-29 Oct. 2008

Firstpage

934

Lastpage

937

Abstract

In this work the Broad-Band Mach-Zehnder Interferometry (BB-MZI) is presented as an alternative operation principle for optical biochemical sensors that will allow for ultra-sensitive, label-free, multi-analyte detection schemes. Simulation studies were performed for a Si-based MZI so as to explore its sensing capabilities in terms of the transmission output spectrum. The presented simulation results concern biochemical applications such as aqueous glucose solutions and hypothetical thin protein adlayers adsorbed on the sensing arm.

Keywords

Mach-Zehnder interferometers; biochemistry; biosensors; chemical sensors; molecular biophysics; proteins; sugar; Si-based MZI; aqueous glucose solution; broadband Mach-Zehnder interferometry; hypothetical thin protein adlayers; label-free biochemical sensing; multianalyte detection scheme; optical biochemical sensors; transmission output spectrum; Biomedical optical imaging; Biosensors; Optical interferometry; Optical refraction; Optical ring resonators; Optical sensors; Optical surface waves; Optical variables control; Optical waveguides; Refractive index;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2008 IEEE

Conference_Location

Lecce

ISSN

1930-0395

Print_ISBN

978-1-4244-2580-8

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2008.4716594

Filename

4716594