Title :
Mechanisms of Anti-Inflammatory Effects of Low-Intensity Extremely High-Frequency Electromagnetic Radiation
Author :
Gapeyev, A.B. ; Mikhailik, E.N. ; Chemeris, N.K.
Author_Institution :
Inst. of Cell Biophys. of Russian Acad. Sci. Pushchino, Moscow
Abstract :
Using a model of acute zymosan-induced inflammation in NMRI mice, the dependence of anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation (EHF EMR) on frequency and intensity was found. The maximum decrease in footpad edema and hyperthermia by 20% was revealed at frequencies of 42.2, 51.8 and 65 GHz, intensity of 0.1 mW/cm2 and exposure duration of 20 min. The pharmacological analysis has shown that arachidonic acid metabolites and histamine are involved in realization of anti-inflammatory effects of low-intensity EHF EMR.
Keywords :
biological NMR; biological effects of microwaves; anti-inflammatory effects; arachidonic acid metabolites; extremely high-frequency electromagnetic radiation; footpad edema; frequency 42.2 GHz to 65 GHz; hyperthermia; time 20 min; zymosan-induced inflammation; Electromagnetic radiation; Frequency; In vitro; In vivo;
Conference_Titel :
Microwave & Telecommunication Technology, 2007. CriMiCo 2007. 17th International Crimean Conference
Conference_Location :
Crimea
Print_ISBN :
978-966-335-012-7
DOI :
10.1109/CRMICO.2007.4368614
