Title :
Noncontact transportation of DNA molecule by dielectrophoretic force for micro DNA flow system
Author :
Morishima, Keisuke ; Fukuda, Toshio ; Arai, Fumihito ; Matsuura, Hideo ; Yoshikawa, Kenichi
Author_Institution :
Dept. of Micro Syst. Eng., Nagoya Univ., Japan
Abstract :
In this paper, we propose a new approach to noncontact transportation of DNA molecules by dielectrophoretic force and the idea of the micro DNA flow system. Such system can be made by using microfabrication technology. At first, we designed a simple micro electrode-flow system and carried out experiments. Experimental demonstration of DNA transportation using dielectrophoretic force and direct observation of the DNA molecule in a nonuniform electric field was carried out with fluorescence microscopy. We showed a simple electrode design and the possibility of noncontact transportation of DNA molecules based on micro DNA flow system. In future we consider the possibility of the micro DNA flow system as one of the biomanipulation and automation systems for DNA sequencing
Keywords :
DNA; electrophoresis; materials handling; molecular biophysics; DNA molecule; DNA sequencing; automation systems; biomanipulation; dielectrophoretic force; fluorescence microscopy; micro DNA flow system; micro electrode-flow system; noncontact transportation; nonuniform electric field; Bioinformatics; Cells (biology); DNA; Dielectrophoresis; Genomics; Humans; Microelectrodes; Micromechanical devices; Organisms; Transportation;
Conference_Titel :
Robotics and Automation, 1996. Proceedings., 1996 IEEE International Conference on
Conference_Location :
Minneapolis, MN
Print_ISBN :
0-7803-2988-0
DOI :
10.1109/ROBOT.1996.506493