Statistical dosimetry analysis in whole-body exposure setup based on rat´s activity behavior

For a whole-body exposure setup of rats, the rats can freely move in the cage in most cases. In order to determine the specific absorption rate (SAR) variation during the entire exposure period, a statistical analysis for the rat activity behavior in the exposure period is necessary. In this study, we divide the rat cage in the exposure box into nine small areas, and derive the stay frequency of rat in each area based on the classification of the documentary photos of rat activity. Using the stay frequency as a weighting factor, we calculate the statistical characteristics of the whole-body average SAR for the rats during the entire exposure period. Such an approach gives a high quality determination of the exposure level.