Transformations and algorithms in a computerized brain atlas

The computerized brain atlas constructed at the Karolinska Hospital, Stockholm, Sweden has been further developed. This atlas was designed to be employed in different fields of neuro imaging such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), and magnetic resonance imaging (MR). The main objectives with the atlas are to aid the interpretation of functional images by introducing anatomical information, to serve as a tool in the merging of data from different imaging modalities, and to facilitate the comparisons of data from different individuals by allowing for anatomical standardization of individual data. The authors describe the algorithms and transformations used in the implementation of the atlas software